Table 2.
Transcripts found to be activity-dependent in multiple studies.
| Gene Symbol | Cell type | Earliest response | Activity response | Reference # |
|---|---|---|---|---|
| Bace1 | mOSN | 10 days | Down | 12,14 |
| Calb2 | mOSN | 6 days | Down | 1,2,11,13 |
| Cdh15 | mOSN | >14 days | Down | 4,13 |
| Chil3 | ? | 25 days | Down | 1,13 |
| Cnga2 | mOSN | 10 days | Up | 1,12 |
| Cyp26b1 | mOSN | 2 days | Up | 6,10,11,12 |
| Dlg2 | mOSN | 25 days | Up | 1,13 |
| Efna5 | mOSN | 2 days | Down | 1,5,6,8,11,13 |
| Entpd2 | mOSN | 6 days | Down | 11,13 |
| Epha5 | mOSN | 2 days | Up | 8,11 |
| Etv3 | mOSN | 6 days | Down | 1,11 |
| Etv5 | mOSN | 25 days | Up | 4,13 |
| Fos | mOSN | 6 days | Up | 11,13 |
| Gpr158 | mOSN | 6 days | Up | 2,13 |
| Kirrel2 | both | 30–40 min | Up | 2,4,5,6,8,9,11,13 |
| Kirrel3 | mOSN | 2 days | Down | 1,2,8, 9,11,13 |
| Lrrc3b | mOSN | 30–40 min | Up | 1,2,11,12,13 |
| Nphs1 | mOSN | 6 days | Up | 2,11 |
| Nrp1 | both | 2 days | Up | 3,4,6,11 |
| Nxph3 | mOSN | 6 days | Up | 3,11 |
| Pcdh10 | mOSN | 6 days | Up | 2,9,11,13 |
| Pcp4l1 | mOSN | 6 days | Up | 1,2,3, 4,11,13 |
| Plxna3 | mOSN | >14 days | Up | 3,4 |
| Ppp3ca | mOSN | 25 days | Down | 1,13 |
| Ptchd1 | mOSN | 6 days | Up | 1,11,13 |
| Ptprn | mOSN | 6 days | Up | 2,3,4,11 |
| Rasgrp4 | mOSN | 6 days | Up | 2,11 |
| Rims3 | mOSN | 6 days | Down | 11,13 |
| S100a5 | mOSN | 30–40 min | Up | 1,2,4,8,11,12,13 |
| Sema3e | mOSN | 6 days | Up | 11,13 |
| Sema7a | mOSN | 6 days | Up | 1, 11 |
| Slc8a1 | mOSN | 6 days | Up | 1,2,11,13 |
| Slc17a6 | mOSN | 6 days | Up | 1, 2 |
| Snca | mOSN | 25 days | Up | 1,13 |
| Syt4 | mOSN | 6 days | Up | 4,11,13 |
The mRNAs from these genes are significant in at least 2 independent studies. Cell type: both, immature and mature OSN; mOSN, mature OSN; Other, cell types other than OSNs;?, unknown. References: 1. (Bennett et al. 2010), 2. (Fischl et al. 2014), 3. (Imai et al. 2006), 4. (Imai et al. 2009), 5. (Kaneko-Goto et al. 2008), 6. (Oztokatli et al. 2012), 7. (Santoro and Dulac 2012), 8. (Serizawa et al. 2006), 9. (Williams et al. 2011), 10. (Login et al. 2015b), 11. Unpublished UNO RNA-seq data (W.B. Titlow and T.S. McClintock; Gene Expression Omnibus accession number GSE89460), 12. (Login et al. 2015a), 13. (Coppola and Waggener 2012), 14. (Cao et al. 2012).