Table 6.
Over-represented annotation ontologies.
| Ontology term | Enrichment score | # of genes |
|---|---|---|
| Expressed in mature OSNs | ||
| Synapse (5) | 4.3 | 36 |
| Membrane proteins (10) | 2.8 | 200 |
| Phosphatidylinositol signaling (4) | 2.5 | 9 |
| Cation channels, transporters (21) | 2.0 | 47 |
| Calmodulin binding (3) | 1.9 | 11 |
| Calcium binding proteins (12) | 1.7 | 15 |
| Endoplasmic reticulum (3) | 1.7 | 33 |
| Nucleotydiltransferase (3) | 1.6 | 6 |
| Cyclic nucleotide-related proteins (31) | 1.5 | 10 |
| Increased by OSN activity | ||
| Synapse (5) | 6.5 | 32 |
| Membrane glycoproteins (19) | 3.7 | 160 |
| Cation channels, transporters (21) | 1.9 | 39 |
| Axon guidance (3) | 1.9 | 11 |
| Differentiation/development (4) | 1.6 | 27 |
| MAPK signalling (11) | 1.6 | 10 |
| Sterile alpha motif domain (4) | 1.6 | 5 |
| Decreased by OSN activity | ||
| Calcium binding proteins (13) | 1.4 | 22 |
| Endoplasmic reticulum (5) | 1.3 | 18 |
DAVID functional bioinformatics analysis. Enrichment scores >1.3 identify significantly overrepresented clusters of annotation terms. Numbers in parentheses are the number of related terms grouped together under one heading.