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. 2018 Feb 28;15(4):3874–3882. doi: 10.3892/etm.2018.5901

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Copyright: © Chang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Immunohistochemical analysis of Wnt-1 and β-catenin expression in the kidney tissues of rats from the Control (n=10), DM (n=10), TW8 (n=10), TW16 (n=11) and Irbesartan (n=10) groups. The expression of Wnt-1 and β-catenin in the kidney tissues of individual rats were determined by (A) immunohistochemistry and (B) quantitatively analyzed. Data are representative images of the kidney tissues of each group of rats (magnification, ×400). ^##P<0.01 vs. Control group; **P<0.01 vs. DM group. GSK, glycogen synthase kinase; NF, nuclear factor; TGF, transforming growth factor; DM, diabetes mellitus; TW8, 8 mg/kg Tripterygium wilfordii; TW16, 16 mg/kg Tripterygium wilfordii.