Table 1. Kinetic parameters for wild-type and 5FWβPGM with native substrate and competitive inhibitors.

	Wild-type βPGM	5FWβPGM
K m	9.0 ± 0.7 μM	10.1 ± 2.1 μM
k cat	7.7 ± 0.1 s–1	3.8 ± 0.1 s–1
IC50 (βG1CP)	18 ± 3 μM	13 ± 5 μM
IC50 (βG1CFsP)	15 ± 2 μM	11 ± 2 μM
K i(comp) (βG1CP)		4.67 ± 0.04 μM
K i(comp) (βG1CFsP)		4.03 ± 0.03 μM