Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters
| Parameters | Result
|
||
|---|---|---|---|
| Group 1 (AGM suspension) | Group 2 (marketed formulation) | Group 3 (AGM–NLC) | |
| Cmax (µg/mL) | 0.35±0.2 | 0.43±0.13 | 0.58±0.2 |
| Tmax (hour) | 1.5 | 1.5 | 2.25 |
| AUC0→t (µg*h/mL) | 633±0.2 | 772±0.29 | 4,357±0.24 |
Note: Data presented as mean ± SD.
Abbreviations: AGM, agomelatine; NLC, nanostructured lipid carrier.
