Figure 2.

Effect of curcumin on follicular development in the POF model. Follicles were observed after H&E staining (A, B, C, D, E and F). The follicle classification was based on the characteristics proposed by Hirshfield and Midgley. (G) Primordial follicle ratio counting was performed in the three groups. Ten mice per group were examined. The primordial follicle ratio refers to the percentage of the primordial follicle number to the total follicle number. (H) The numbers of those follicles at different developmental stages of maturation were summarized. *P < 0.05 and **P < 0.01 vs the control group, ^# P < 0.05 and ^## P < 0.01 vs the d-gal group.