Table 3.
Comparison of the serum IL-37 levels according to disease manifestations in 62 patients with adult-onset Still’s disease
| Manifestations | Serum IL-37 levels | P value | |
|---|---|---|---|
| Fever | (+), n = 38 | 428.42 ± 291.40 | 0.0003 |
| (−), n = 24 | 165.33 ± 221.06 | ||
| Sore throat | (+), n = 30 | 419.32 ± 294.61 | 0.0127 |
| (−), n = 32 | 239.64 ± 270.42 | ||
| Skin rash | (+), n = 34 | 416.33 ± 308.19 | 0.0041 |
| (−), n = 28 | 217.60 ± 239.06 | ||
| Lymphadenopathy | (+), n = 32 | 436.64 ± 288.01 | 0.0005 |
| (−), n = 30 | 209.18 ± 256.72 | ||
| Hepatomegaly | (+), n = 1 | 156.63 | 0.7586 |
| (−), n = 61 | 329.37 ± 295.93 | ||
| Splenomegaly | (+), n = 15 | 477.52 ± 311.97 | 0.015 |
| (−), n = 47 | 278.41 ± 274.67 | ||
| Pericarditis | (+), n = 8 | 432.69 ± 301.64 | 0.1824 |
| (−), n = 54 | 310.86 ± 292.79 | ||
| Pneumonia | (+), n = 20 | 379.57 ± 310.59 | 0.3544 |
| (−), n = 42 | 301.34 ± 286.62 | ||
| Pleuritis | (+), n = 10 | 479.63 ± 336.37 | 0.0978 |
| (−), n = 52 | 297.15 ± 279.57 | ||
| Myalgia | (+), n = 14 | 449.08 ± 222.11 | 0.0211 |
| (−), n = 48 | 290.85 ± 304.96 | ||
| Arthritis | (+), n = 18 | 427.91 ± 324.91 | 0.1068 |
| (−), n = 44 | 285.13 ± 274.02 | ||
| Arthralgia | (+), n = 38 | 405.41 ± 297.41 | 0.0026 |
| (−), n = 24 | 201.77 ± 246.81 | ||
IL Interleukin
Serum IL-37 levels are shown as mean ± SD, and differences between two groups were analyzed using the Mann-Whitney U test for nonparametric data