Figure 6.
STAT1−/− antigen presenting cells favor Type 17 immune polarization. WT or STAT1−/− bone marrow derived dendritic cells were incubated with OTII naïve ovalbumin-specific T cells for 5 days in the presence of ovalbumin peptide with or without preceding challenge with heat-killed MRSA. Cytokine levels were determined by Bioplex assay (n = 6–8). SA = heat-killed MRSA, CNT = control. *p < 0.05 WT vs. STAT1, †p < 0.05 SA vs. CNT