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. 2018 Mar 22;13(3):e0194896. doi: 10.1371/journal.pone.0194896

Fig 7. HPLC analysis of dopamine and its metabolites.

Fig 7

A-C) After unilateral injections of MPP+ in the striatum, the ipsilateral striatum shows a significant reduction in the concentration of DA (A), HVA (B) and DOPAC (C) compared to the contralateral hemisphere (Aqp9-/-, n = 6; WT, n = 6). The ipsilateral reduction in HVA is significantly more pronounced in WT mice than in Aqp9-/- mice (p = 0.038). Corresponding p-values for DA and DOPAC are 0.063 and 0.059, respectively. Bars are mean ± 2 SEM; *p<0.05, ** p<0.01, ***p<0.001.