Inhibitory versus stimulatory effects of AUD on relative lipid ion expression in the (A, C, E) BA4 and (B, D, F) BA8/9 regions of human frontal lobe WM. Results in Figure 2 are summarized and graphically displayed to compare the percentages of (A, B) sphingolipids and phospholipids, (C, D) sulfatides and ceramides, and (E, F) different phospholipid subtypes that were significantly increased, unchanged, or significantly decreased in AUD relative to control samples. Data were analyzed using Chi-square tests and corresponding P-values are shown within the panels. Phosphatidylcholine was not detected in the negative ionization mode of mass spectrometry.