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. 2018 Mar 21;38(12):2923–2943. doi: 10.1523/JNEUROSCI.1532-17.2018

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Copyright © 2018 the authors 0270-6474/18/382923-21$15.00/0

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Figure 8. — Subretinal hUTC transplantation preserves OPL synapses in RCS rats. Representative images of the OPL with the PR ribbon synapses labeled for (A) Bassoon (green) and mGluR6 (red) and (B) Bassoon (green) and α2δ-1 (red) from LE (control), RCS + BSS, and RCS + hUTC P21 and P60 retinas on P95. Quantification of the number of synapses in the OPL revealed that hUTC transplantation protected (C) ribbon synapses. D, Particularly, α2δ-1-containing synapses were specifically preserved following hUTC treatment. Data were obtained from a minimum of 3 animals of either sex and expressed as mean ± SEM. ***p < 0.0001.