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. 2015 Feb 22;71(3):281–289. doi: 10.1093/gerona/glv010

Figure 3.

Figure 3.

Messenger ribonucleic acid (mRNA) levels in striatum of growth hormone receptor gene disrupted or knock out (black bars) and normal aging (white bars) mice. mRNA expression levels of IKKβ, NFκB-p50, NFκB-p65, IL-1β, IGF-1, IGF-1R, VGLUT1, VGLUT3, GLAST, GLT-1, GluN2B, and GluA1 in the striatum of 4- to 6-, 8- to 10-, and 20- to 22-month-old mice. Two-way analysis of variance with a Fisher’s least significant difference post hoc analysis ( n = 5–9 mice per group). * p < .05, ** p < .01, *** p < .001, and **** p < .0001 indicate significance between ages within the same genotype. # p < .05, ## p < .01, ### p < .001, and #### p < .0001 indicate significance between age-matched genotypes.