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. 2017 Dec 13;25(4):661–676. doi: 10.1038/s41418-017-0005-3

Fig. 6. APP deficiency suppresses the upregulation of JNK3 expression and JNK function in mouse retina after ONA.

Fig. 6

a Representative western blots show JNK3 expression and overall phosphorylative activation of JNK in retinae from wild-type or APP-null mice 1 day (1 d), 1 week (1 w) and 2 weeks (2 w) after ONA (n = 3 for each time point). Anti-JNK3, anti-pJNK and anti-GAPDH antibodies were used to detect the respective protein expression. b The bar charts show quantitative analysis of relative JNK3 expression or overall phosphorylative activation of JNK in the ipsilateral-injured retinae vs. the contralateral-uninjured retina. One-way ANOVA followed by post-hoc Bonferroni test: **p < 0.01. Error bars represent SEM