Fig. 4.

Prophages are spontaneously induced in active commensal lysogens. a The percentage of induced prophages and active lysogenic bins estimated by mapping phage metagenomic reads to the prophage sequences. b The taxonomic profiles of lysogenic and active lysogenic bins compared at the phylum level (n = 24). The composition of induced prophages for different diets determined using c the Jaccard dissimilarity-based PCoA (Adonis; FORTH, P = 0.001; BACK, P = 0.057) and d Jaccard distance comparisons (one-way ANOVA; FORTH, P < 0.001; BACK, P = 0.006). All data are presented as the mean ± SEM. LFD low-fat diet, HFHS high-fat, high-sucrose diet, and LFPP low-fat, high-plant-polysaccharide diet