Fig. 3. Full-length Mcl-1 also binds more Bak after Bid than after Bid^Bim.

a Diagram showing interactions between the Bcl-2 family members in the tripartite mixtures tested. b Mouse liver mitochondria (MLM) from Mcl-1^flox/flox mice were treated with Bid or Bid^Bim at the indicated concentrations. Samples were assessed as in Fig. 1. Blots are from the same experiment, representative of two independent experiments. Note that any Bid or Bid^Bim co-immunoprecipitated with Mcl-1 (MODE 1) was below the limits of detection and therefore not shown.