Fig. 3.

Paenibacillaceae resistomes do not cluster by phylogeny. 15 resistance enzymes and the vanA operon were compared across a family phylogeny of 184 Paenibacillaceae isolates. The tree is presented as a dendrogram. Resistance enzymes were identified in this study, or in the experimental validation of the Paenibacillus sp. LC231 resistome [9]. The functions of each resistance enzymes not identified in this study are; Llm lincosamide resistance methyltransferase; Vat streptogramin A acetyltransferase, Cpa capreomycin acetyltransferase, AAC(2′) kasugamycin acetyltransferase, Bah bacitracin amidohydrolase, Vgb streptogramin B lyase. The complete family phylogeny is found in Supplementary Fig. 5