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Progression of the number of canonical proteins (using HPP Guidelines metrics) of historical Plasma PeptideAtlas builds. Builds since 2009 (in blue) do not contain N-glycosylation enriched datasets and were thresholded at a ~1% protein-level FDR prior to application of guideline 15 requirements. Builds prior to 2009 (in orange) contain N-glycosylation enriched datasets and were thresholded at a distinct peptide probability ≥ 0.9 prior to application of guideline 15 requirements.
