Table 2.

Basic characteristics of E-MECHANIC participants.

Variable		E-MECHANIC Group (N=90 total)
		Control N=29	8 KKW N=33	20 KKW N=28
Male/Female (N)		9/20	6/27	8/20
White (%)		72	67	71
Age (yrs)		50.2 ± 11.0	48.9 ± 10.7	45.7 ± 13.9
Cholesterol medication use, N (%)	Baseline	5 (17%)	3 (9%)	3 (11%)
	Post-training	6 (21%)	3 (9%)	3 (11%)
Weight (kg)	Baseline	90.3 ± 15.4	90.7 ± 17.4	83.4 ± 13.8
	Delta	0.4 ± 3.5	0.3 ± 2.9	−1.4 ± 3.1*
BMI (kg/m2)	Baseline	32.4 ± 4.6	32.2 ± 4.9	29.9 ± 4.4
	Delta†	0.2 ± 1.2	0.07 ± 1.0	−0.5 ± 1.1*
HDL-C (mg/dl)	Baseline	58 ± 15	60 ± 15	57 ± 20
	Delta	−2 ± 7	−1 ± 8	1 ± 6
TG (mg/dl)	Baseline	117 ± 57	106 ± 45	98± 50
	Delta	−3 ± 49	−10 ± 39	−1 ± 30
Total Cholesterol (mg/dl)	Baseline	209 ± 27	199 ± 35	189 ± 40
	Delta	−16 ± 31	−2 ± 17	2 ± 20
3H efflux (Global)	Baseline	0.87 ± 0.2	0.82 ± 0.2	0.83 ± 0.2
	Delta	−0.03 ± 0.1	0.01 ± 0.2	−0.01 ± 0.1
BODIPY efflux	Baseline	0.94 ± 0.3	0.87 ± 0.3	0.86 ± 0.3
	Delta	−0.08 ± 0.2	−0.06 ± 0.2	−0.03 ± 0.3
HAE	Baseline	63.3 ± 12.3	62.4 ± 8.6	60.7 ± 12.7
	Delta	−2.4 ± 9.0	1.4 ± 8.8	0.9 ± 11.1

Data represented as mean ± SD. Delta = post-training value – baseline value.

^*p<0.05 for within group training response (paired t-test of difference from baseline).

^†p=0.04 for differences in mean values between groups. Mean value for 20 KKW group significantly different from control and 8 KKW groups.

BMI, body mass index; TG, triglycerides.