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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Steroids. 2017 Nov 21;133:8–14. doi: 10.1016/j.steroids.2017.11.007

Figure 2.

Figure 2

The expression of Mediator subunits is altered in prostate cancer and breast cancer. A. Expression of each Mediator subunit in 85 prostate adenocarcinoma complete tumor samples with sequencing, CNA, and mRNA data from Taylor, et al, 2010. Several Mediator subunits, such as MED19, show consistent mRNA upregulation (1.5-fold or greater). In the case of MED19 this is correlated with poor outcome. B. Expression of each Mediator subunit in 816 breast adenocarcinoma complete tumor samples with sequencing, CNA, and mRNA data from Ciriello, et al, 2015. Several Mediator subunits, such as MED1 or MED30, show mRNA upregulation (1.5-fold or greater) or amplification. In the case of MED1 this is correlated with poor outcome.