Table 1.
Mediator Subunits in Humans
Module | Subunit |
---|---|
Head | MED6 |
MED8 | |
MED11 | |
MED17 | |
MED18 | |
MED20 | |
MED22 | |
MED28 | |
MED30 | |
Middle | MED1 |
MED4 | |
MED7 | |
MED9 | |
MED10 | |
MED19 | |
MED21 | |
MED26 | |
MED31 | |
Tail | MED15 |
MED16 | |
MED23 | |
MED25 | |
MED27 | |
MED29 | |
Kinase | MED12 |
MED12L | |
MED13 | |
MED13L | |
CDK8 | |
CDK19 | |
CCNC | |
Backbone | MED14* |
Bold = human-specific subunits
Originally considered a middle subunit; re-classified as a backbone/scaffold subunit that contacts and holds together the head, middle, and tail modules