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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Steroids. 2017 Nov 21;133:8–14. doi: 10.1016/j.steroids.2017.11.007

Table 1.

Mediator Subunits in Humans

Module Subunit
Head MED6
MED8
MED11
MED17
MED18
MED20
MED22
MED28
MED30
Middle MED1
MED4
MED7
MED9
MED10
MED19
MED21
MED26
MED31
Tail MED15
MED16
MED23
MED25
MED27
MED29
Kinase MED12
MED12L
MED13
MED13L
CDK8
CDK19
CCNC
Backbone MED14*

Bold = human-specific subunits

*

Originally considered a middle subunit; re-classified as a backbone/scaffold subunit that contacts and holds together the head, middle, and tail modules