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. 2018 Feb 12;5(1):79–88. doi: 10.14744/nci.2017.10692

Table 2.

Summary of studies involving fecal microbiota transplantation and inflammatory bowel disease

Author, year Method Mode of FMT Delivery n Outcome
Borody et al., 1989 [38] Case series Not reported 2 Positive
Borody et al., 2003 [39] Case series Enema 6 Clinical & endoscopic remission at 1 year
Angelberger et al., 2013 [50] Cohort study Nasojejunal infusion & enema 5 Positive
Kump et al., 2013 [51] Cohort study Colonoscopy 6 Positive
Kunde et al., 2013 [52] Cohort study Enema 10 33% clinical response at 1 month
Danman et al., 2014 [53] Cohort study Colonoscopy 5 20% clinical response
Cui et al., 2015 [47] Cohort study Nasogastric infusion 14 57% clinical improvement
Cui et al., 2015 [49] Cohort study Nasogastric infusion 30 86.6% clinical remission at 30 days
Moayyedi et al., 2015 [39] RCT Enema 65 24% achieved remission
Rossen et al., 2015 [78] RCT Autologous stool 48 No significant effect
Suskind et al., 2015 [46] Cohort study Nasogastric infusion 9 78% clinical remission
Wei et al., 2015 [54] Cohort study Colonoscopy (ulcerative colitis), nasojejunal infusion 14 Clinical improvement
(Crohn’s disease)
Paramsothy et al., 2016 [43] RCT Enema 81 30% remission achieved
Uygun et al., 2017 [48] Cohort study Colonoscopy 30 70% improved symptoms, 43.3% clinical&endoscopic remission

FMT: Fecal microbiota transplantation; RCT: Randomized controlled trial.