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[a] Interatomic interactions of rifampin (orange) with the β subunit of RNAP. All the interacting and proximal residues were depicted. The black dashed lines indicate hydrogen bonding interactions and green dashed lines indicate hydrophobic interactions. [b] Hydrogen bonds (black dashed lines) between rifampin and sidechains of R454, R465 and N493, and the mainchain of Q438 and F439.
