Table 2.
Genetic testing under the dominant and recessive models*
| Gender | Group | Dominant | X2 | P (df=1) | OR (95% CI) | Power | Recessive | X2 | P (df=1) | OR (95% CI) | Power |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GG+GC CC | GG GC+CC | ||||||||||
| All | Cases | ||||||||||
| (n=874) | 397 477 | 56 818 | |||||||||
| Controls | |||||||||||
| (n=776) | 284 492 | 13.209 | 2.81’10–4 | 1.442 (1.183-1.757) | 0.999 | 32 744 | 4.246 | 0.039 | 1.592 (1.019-2.485) | 0.787 | |
| Males | Cases | ||||||||||
| (n=625) | 278 347 | 40 585 | |||||||||
| Controls | |||||||||||
| (n=424) | 145 279 | 11.098 | 0.001 | 1.542 (1.194-1.990) | 0.997 | 15 409 | 4.166 | 0.041 | 1.864 (1.016-3.420) | 0.670 | |
| Females | Cases | ||||||||||
| (n=249) | 119 130 | 16 233 | |||||||||
| Controls | |||||||||||
| (n=352) | 139 213 | 4.103 | 0.043 | 1.403 (1.011-1.947) | 0.817 | 17 335 | 0.716 | 0.397 | 1.353 (0.670-2.733) | 0.300 |
*
P value less than or equal to 0.05 is in bold. 95%CI-95% confidence interval; OR - odds ratio