Table 3.
Comparison of genotype and allele frequencies between cases and controls by age*
| Age | Group | Genotype(counts) | X2 | P (df=2) | HWE | Allele (n,%) | X2 | P (df=1) | OR (95% CI) | Power | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GG | GC | CC | G | C | |||||||||
| 55< | Cases | ||||||||||||
| (n=186) | 7 | 70 | 109 | 0.404 | 84 (22.6) | 288 (77.4) | |||||||
| Controls (n=236) | 10 | 77 | 149 | 1.156 | 0.561 | 1.000 | 97 (20.6) | 375 (79.4) | 0.509 | 0.476 | 1.128 (0.811-1.569) | 0.111 | |
| 55-65 | Cases | ||||||||||||
| (n=361) | 27 | 149 | 185 | 0.796 | 203 (28.1) | 519 (71.9) | |||||||
| Controls (n=357) | 15 | 125 | 217 | 8.056 | 0.018 | 0.641 | 155 (21.7) | 559 (78.3) | 7.876 | 0.005 | 1.411 (1.109-1.795) | 0.803 | |
| >65 | Cases | ||||||||||||
| (n=327) | 22 | 122 | 183 | 0.768 | 166 (25.4) | 488 (74.6) | |||||||
| Controls (N=183) | 7 | 50 | 126 | 8.426 | 0.015 | 0.446 | 64 (17.5) | 302 (82.5) | 8.377 | 0.004 | 1.605 (1.163-2.215) | 0.835 | |
*
P value less than or equal to 0.05 is in bold. 95%CI-95% confidence interval; HWE-Hardy Weinberg equilibrium; OR-odds ratio