Table 2.
Variations of laboratory parameters before and after isoquercetin in patients on sunitinib –*; ° Wilcoxon test for paired samples.
| Laboratory test—Unit of measure | Visit 1 Mean ± Standard deviation | Visit 4 Mean ± Standard deviation | P-value T-test for paired sample |
|---|---|---|---|
| Hemoglobin (g/dl) | 13.8 ± 1.7 | 13.7 ± 2 | 0.876 |
| Neutrophils (per mm3) | 2.8 ± 1 | 2.5 ± 0.5 | 0.457 |
| Lymphocytes (per mm3) | 1.7 ± 0.4 | 1.7 ± 0.6 | 0.898 |
| Platelet (per mm3) | 233.1 ± 83.1 | 241.2 ± 79.2 | 0.750 |
| FT3 pg/ml | 2.7 ± 0.6 | 2.8 ± 0.5 | 0.807 |
| Creatinin (mg/dL) | 1.3 ± 0.2 | 1.4 ± 0.4 | 0.526 |
| Total bilirubin (mg/dl) | 0.7 ± 0.4 | 0.6 ± 0.3 | 0.712 |
| SODIUM (mEq/L) | 139.5 ± 4.1 | 139.6 ± 4 | 0.913 |
| POTASSIUM (mEq/L) | 4.6 ± 0.4 | 4.4 ± 0.4 | 0.142 |
| CHLORIDE (mEq/L) | 102.7 ± 1.6 | 103.2 ± 3.5 | 0.749 |
| Visit 1 Median (25th; 75th percentile) | Visit 4 Median (25th; 75th percentile) | P-value Wilcoxon test for paired samples | |
| GGT (IU/L) | 33 (19; 50.8) | 26 (18; 54) | 0.172 |
| TSH (mIU/L) | 3.9 (1.3; 12.6) | 4 (1.5; 12.4) | 0.859 |
| Glycemia (mg/dL) | 97.5 (86.8; 117.3) | 85 (76; 104.5) | 0.093 |
| AST (IU/L) | 23.5 (20.5; 41) | 27 (22; 34) | 0.444 |
| ALT (IU/L) | 27.5 (15.3; 34.3) | 23 (18; 38) | 0.964 |