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. 2018 Mar 22;9(4):432. doi: 10.1038/s41419-018-0409-0

Fig. 4. Overexpression of BPIFB1 impaired VTN-induced nasopharyngeal carcinoma cell cycle arrest after irradiation.

Fig. 4

Flow cytometry was performed to assess variations in cell cycle distribution. a BPIFB1 overexpression resulted in G0/G1 phase arrest, and VTN overexpression resulted in G2/M phase arrest in CNE2 and HONE1 cells after irradiation. The four groups of cells (overexpressing BPIFB1, VTN, both, and the control group) were incubated for 24 h after treatment with 6 Gy of radiation. b Histogram of cell cycle distribution of CNE2 and HONE1 cells. Data represent means ± SD from of at least three independent experiments; *P < 0.05; **P < 0.01; NS, no significance