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. 2018 Mar 16;12:154. doi: 10.3389/fnins.2018.00154

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Copyright © 2018 Nardecchia, Orlando, Iacovelli, Colamartino, Fiori, Leuzzi, Piccinin, Nistico, Puglisi-Allegra, Di Menna, Battaglia, Nicoletti and Pascucci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The increase in mGlu5 receptor protein levels found in ENU2 mice is gender-dependent. Immunoblot analysis of mGlu5 receptors in the hippocampus of female ENU2 (n = 4) and heterozygous (HTZ, n = 7) mice is shown in (A). Comparison between male (n = 3) and female (n = 4) ENU2 mice is shown in (B). Densitometric values are means ± S.E.M. In (B), ^*p < 0.05 vs. male ENU2-values [Student's t-test; t₍₅₎ = 4.75].