Table 2.
List of downregulated genes of UA159 in the presence of S-PRG eluate, which were observed in both MT8148 and UA159 under three different conditions using DNA microarray analysis.
Gene | Accession number | S-PRG 0% | S-PRG 6.3% | S-PRG12.5% | S-PRG 25.0% | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Signal | Signal | Log2* | Change# | Signal | Log2* | Change# | Signal | Log2* | Change# | ||
clp | 721354.1 | 18865.6 | 6619.2 | −1.51 | 0.351 | 2873.2 | −2.71 | 0.152 | 3817.9 | −2.30 | 0.202 |
gldA | 720934.1 | 55312.5 | 21392.5 | −1.37 | 0.387 | 9103.4 | −2.60 | 0.165 | 2217.9 | −4.64 | 0.040 |
pdhA | 721781.1 | 30983.4 | 7458.1 | −2.06 | 0.241 | 547.5 | −5.82 | 0.018 | 151.5 | −7.68 | 0.005 |
pdhB | 721780.1 | 26341.2 | 5687.7 | −2.21 | 0.216 | 283.9 | −6.53 | 0.011 | 131.4 | −7.69 | 0.005 |
pdhC | 721779.1 | 32996.4 | 7188.0 | −2.20 | 0.218 | 320.5 | −6.69 | 0.010 | 128.0 | −8.01 | 0.004 |
pdhD | 721782.1 | 5817.6 | 1717.4 | −1.76 | 0.295 | 250.6 | −4.54 | 0.043 | 47.4 | −6.95 | 0.008 |
pfl2 | 720932.1 | 11402.1 | 3593.0 | −1.67 | 0.315 | 2135.1 | −2.42 | 0.187 | 1288.9 | −3.14 | 0.113 |
phsG | 721879.1 | 41481.6 | 17147.4 | −1.27 | 0.413 | 8112.9 | −2.35 | 0.196 | 1380.1 | −4.91 | 0.033 |
*Log2 means Log2 ratio. #Change means Fold change. The Log2 ratio and Fold change were calculated by signal with each concentration of S-PRG eluate/signal without S-PRG eluate.