Table 4.
List of downregulated genes of UA159 in the presence of S-PRG eluate, which were observed in both MT8148 and UA159 under two different conditions using DNA microarray analysis.
| Gene | Accession number | S-PRG 0% | S-PRG 6.3% | S-PRG12.5% | S-PRG 25.0% | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal | Signal | Log2* | Change# | Signal | Log2* | Change# | Signal | Log2* | Change# | ||
| celR | 721935.1 | 11936.0 | 1137.1 | −3.39 | 0.095 | 366.9 | −5.02 | 0.031 | 38.4 | −8.30 | 0.003 |
| glgA | 721880.1 | 30585.2 | 17989.6 | −0.77 | 0.588 | 10161.1 | −1.59 | 0.332 | 1366.7 | −4.48 | 0.045 |
| glgB | 721883.1 | 18468.0 | 16127.7 | −0.20 | 0.873 | 8708.1 | −1.08 | 0.471 | 932.6 | −4.31 | 0.050 |
| glgC | 721882.1 | 30765.2 | 23441.6 | −0.39 | 0.762 | 10508.8 | −1.55 | 0.342 | 1055.7 | −4.87 | 0.034 |
| glgD | 721881.1 | 134094.9 | 101989.3 | −0.39 | 0.761 | 48072.9 | −1.48 | 0.359 | 5395.6 | −4.64 | 0.040 |
| pfl | 720850.1 | 210979.6 | 166145.4 | −0.35 | 0.787 | 69347.0 | −1.61 | 0.329 | 9805.4 | −4.43 | 0.046 |
| ptcA | 721934.1 | 7508.6 | 633.3 | −3.57 | 0.084 | 207.5 | −5.19 | 0.027 | 17.7 | −8.74 | 0.002 |
| ptcC | 721932.1 | 2921.0 | 366.2 | −3.00 | 0.125 | 124.6 | −4.56 | 0.043 | 38.5 | −6.25 | 0.013 |
| wapA | 721382.1 | 3891.4 | 2323.7 | −0.76 | 0.590 | 1931.4 | −1.01 | 0.496 | 568.7 | −2.77 | 0.146 |
*Log2 means Log2 ratio. #Change means Fold change. The Log2 ratio and Fold change were calculated by signal with each concentration of S-PRG eluate/signal without S-PRG eluate.