Table 1.
Demographic characteristics and laboratory findings of study groups
| Control (n=40) | WCH (n=36) | HT (n=40) | P | |
|---|---|---|---|---|
| Gender, F/M | 23/17 | 18/18 | 23/17 | 0.75 |
| Age, years | 42.4±4.6 | 42.8±7.1 | 44.4±3.9 | 0.21 |
| Disease duration, years | – | 2.3±2.3 | 4.5±2.5 | <0.001 |
| BMI, kg/m2 | 23.6±1.1 | 23.8±1.3 | 23.7±1.3 | 0.82 |
| Glucose, mg/dL | 85.6±5.3 | 88.7±8.8 | 88.2±5.9 | 0.11 |
| Creatinine, mg/dL | 0.7±0.2 | 0.8±0.2 | 0.8±0.3 | 0.13 |
| Uric acid, mg/dL | 4.3±0.9 | 4.6±0.9 | 4.6±0.9 | 0.23 |
| LDL, mg/dL | 108.4±19.9 | 112.1±9.9 | 109.7±17.8 | 0.63 |
| TG, mg/dL | 93.7±27.6 | 104.1±28.1 | 97.1±34.4 | 0.31 |
| HDL, mg/dL | 58.9±13.3 | 53.4±10.5 | 53.9±11.1 | 0.07 |
| CRP, mg/L | 1.5±1.3 | 2.2±1.1 | 2.6±1.1 | <0.001a |
| CrCl, mL/min | 110.8±30.4 | 121.5±29.6 | 117.7±27.6 | 0.27 |
| Office SBP, mm Hg | 122.5±6.7 | 148.9±3.9 | 136.5±4.9 | <0.001b |
| Office DBP, mm Hg | 75.9±5.3 | 95.1±3.7 | 86.5±3.9 | <0.001c |
| Average SBP, mm Hg* | 118.9±8.5 | 118.6±8.4 | 135.1±4.1 | <0.001d |
| Average DBP, mm Hg* | 74.5±5.8 | 74.6±5.3 | 85.4±4.3 | <0.001e |
| Daytime SBP, mm Hg* | 122.4±9.1 | 122.3±8.9 | 139.5±4.2 | <0.001f |
| Daytime DBP, mm Hg* | 67.4±4.1 | 66.8±3.8 | 88.5±6.5 | <0.001g |
| Nighttime SBP, mm Hg* | 110.8±8.3 | 110.7±7.8 | 121.4±6.4 | <0.001h |
| Nighttime DBP, mm Hg* | 67.3±4.1 | 66.8±3.8 | 75.5±6.5 | <0.001i |
All data were expressed as the mean±SD. Normal distribution of data was tested with 1-sample Kolmogorov-Smirnov test. Difference in gender was analyzed using chi-square test. All statistical comparisons were performed using analysis of variance to compare multiple-group means. BMI - body mass index; CRP - C-reactive protein; CrCl - creatinine clearance; DBP - diastolic blood pressure; ESR - erythrocyte sedimentation rate; F - female; HDL - high density lipoprotein; HT - hypertension; LDL - low density lipoprotein; M - male; SBP - systolic blood pressure; TG - triglyceride; WCH - white coat hypertension.
Ambulatory blood pressure monitoring.
Control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and HT, P<0.001; control and WCH, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001;
control and WCH, P<0.001; control and HT, P<0.001; WCH and HT, P<0.001