Table 4.

Sensitivity, specificity, area under curve, cut-off, and asymptotic significance of receiver operating curve analysis of oxidative stress parameters and blood pressure

		Sensitivity (%)	Specificity (%)	AUC	Cut-off	Asymptotic Sig.
Control vs WCH	IMA						86.1	65	0.803	38.9	<0.001
	T-SH	80.6	77.5	0.853	0.75	<0.001
	PAB	72.2	67.5	0.714	0.64	0.001
	PCO	63.9	67.5	0.670	1.07	0.011
Control vs HT	IMA	90	85	0.948	47.8	<0.001
	T-SH	87.5	85	0.926	0.69	<0.001
	AOPP	70	70	0.765	78.1	<0.001
	PAB	85	85	0.934	0.73	<0.001
	PCO	70	70	0.733	1.11	<0.001
	8-OHdG	90	80	0.925	4.71	<0.001
WCH vs HT	IMA	87.5	69.4	0.739	56.1	<0.001
	T-SH	70	61.1	0.691	0.61	0.004
	AOPP	70	69.4	0.708	79.2	0.002
	PAB	77.5	69.4	0.837	0.79	<0.001
	8-OHdG	87.5	75	0.877	5.64	<0.001

To assess diagnostic accuracy, receiver operating characteristic curve analysis was performed. Area under the curve was then estimated. AOPPs - advanced oxidation protein products; AUC - area under curve; HT - hypertension; IMA - ischemia modified albumin; PAB - prooxidant-antioxidant balance; PCO - protein carbonyl; ROC - receiver operating curve; T-SH - total thiol; WCH - white coat hypertension; 8-OHdG-8-hydroxy-2’-deoxyguanosine. Curves were created for all parameters and their cooperative power to discriminate 2 sets of patients, control and WCH groups, controls and HT, and WCH and HT