Table 3.

Comparison of c.63A>G (rs2277923) genotype among secundum atrial septal defect populations

Study reference	Population reference	[A] (A/A) frequency	[G] (G/G or A/G) frequency	P*	A/G** frequency	G/G** frequency (%)	P*
Yu Cao et al., 2016 (48)	Chinese	34/105 (32.4%)	71/105 (67.6%)	0.23	43/71 (60.6%)	28/71 (39.4)	0.17
Posch et al., 2008 (52)	German	69/170 (40.6%)	101/170 (59.4%)	0.74	82/101 (81.2%)	19/101 (18.8)	0.73
Present study	Moroccan	14/32 (43.75%)	18/32 (56.25%)	–	14/18 (77.8%)	4/18 (22.2)	–

^*Compared to present study rate using Fisher’s exact test for smaller cohorts and chi-square test for large cohorts.

^**This column and the adjacent right column indicate respectively the number of heterozygous and homozygous cases among the ASD population carrying the c.63A>G genotype. The percentages show, respectively, the frequency of the carriers of the homozygous and the heterozygous c.63A>G. these columns respectively: Frequency of heterozygous c.63A>G; Frequency of homozygous c.63A>G