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. 2018 Apr 5;28(4):207–213. doi: 10.2188/jea.JE20160191

Table 1. Baseline characteristics of the study participants by daily coffee consumption.

Characteristics Men (n = 41,727) P

No Coffee <1 Cup/day 1–2 Cups/day 3–4 Cups/day ≥5 Cups/day
Number of participants 13,191 12,767 10,414 3,921 1,434  
Number of lung cancer cases 403 370 296 109 49  
Age, years, mean (SD) 53.7 (7.7) 52.0 (7.7) 50.6 (7.8) 48.4 (7.3) 48.9 (7.4) <0.001
Body mass index, kg/m2, mean (SD) 23.5 (2.9) 23.6 (2.8) 23.5 (2.8) 23.4 (2.9) 23.3 (3.1) <0.001
Diabetes, % 8.6 6.3 4.7 4.1 3.9 <0.001
Current smoker, % 43.4 50.0 56.2 69.6 76.9 <0.001
Physical activity almost daily, % 6.1 4.9 4.8 4.3 5.5 <0.001
Dietary intake
 Total energy intake, kcal/day, mean (SD) 1,952 (552) 1,953 (551) 1,901 (516) 1,881 (512) 1,919 (527) <0.001
 Fruits, g/day, mean (SD) 27 (30) 27 (26) 27 (28) 26 (27) 28 (37) <0.001
 Vegetables, g/day, mean (SD) 47 (45) 45 (46) 44 (42) 40 (39) 44 (53) <0.001
 Isoflavone, mg/day, mean (SD) 18 (10) 17 (9) 16 (9) 15 (9) 15 (9) <0.001
 Alcohol consumption, g/week, mean (SD) 205 (218) 186 (209) 174 (201) 157 (197) 154 (220) <0.001
 Green tea >1 time/day, % 75.6 75.2 74.5 70.1 65.1 <0.001
 Chinese tea >1 time/day, % 10.4 8.7 11.8 9.3 10.9 <0.001
 Black tea >1 time/day, % 1.7 1.6 3.2 2.6 3.8 <0.001
Characteristics Women (n = 45,352) P

No Coffee <1 Cup/day 1–2 Cups/day 3–4 Cups/day ≥5 Cups/day
Number of participants 15,202 13,554 12,573 3,155 868  
Number of lung cancer cases 163 139 103 23 13  
Age, years, mean (SD) 55.1 (7.7) 52.4 (7.8) 50.0 (7.5) 47.3 (6.6) 48.2 (7.3) <0.001
Body mass index, kg/m2, mean (SD) 23.7 (3.3) 23.6 (3.1) 23.4 (3.1) 23.2 (3.0) 23.4 (3.2) <0.001
Diabetes, % 4.9 2.5 2.0 1.3 1.3 <0.001
Current smoker, % 4.2 4.0 6.3 13.1 23.6 <0.001
Physical activity almost daily, % 5.8 4.4 4.4 3.2 5.6 <0.001
Dietary intake
 Total energy intake, kcal/day, mean (SD) 1,221 (305) 1,248 (304) 1,247 (296) 1,230 (297) 1,295 (322) <0.001
 Fruits, g/day, mean (SD) 102 (75) 100 (66) 95 (67) 89 (75) 90 (90) <0.001
 Vegetables, g/day, mean (SD) 112 (92) 106 (82) 103 (84) 92 (81) 93 (92) <0.001
 Isoflavone, mg/day, mean (SD) 26 (13) 24 (12) 23 (11) 22 (12) 20 (12) <0.001
 Alcohol consumption, g/week, mean (SD) 10 (54) 11 (54) 11 (50) 17 (82) 19 (58) <0.001
 Green tea >1 time/day, % 77.1 77.8 74.7 66.4 66.6 <0.001
 Chinese tea >1 time/day, % 12.1 11.0 14.0 13.7 20.3 <0.001
 Black tea >1 time/day, % 1.8 1.8 4.5 3.4 5.0 <0.001

SD denotes standard deviation. The body mass index is the weight divided by the square of the height in meters.