FIG 3.

MHC-I-deficient β2m and TAP1-deficient mice have higher levels of serum IFN-γ following infection with NMI. Serum was collected at 14 dpi, and levels of IFN-γ were measured by ELISA. (A) Serum IFN-γ levels from β2m KO mice at 14 dpi. (B) Serum IFN-γ levels from TAP1⁻ mice 14 dpi. These data indicate that serum levels of IFN-γ were higher in both β2m and TAP1 knockout mice following infection with NMI. The data presented for each group are the average with standard deviation for four serum samples. Results were analyzed by t test for statistical significance. *, P < 0.05; **, P < 0.01.