Fig. 1.

Animal survival and physical assessment. a Kaplan Meier curves show that IG treatment increases significantly the lifespan of a group of 45 dko IG treated mice (being 25 females and 20 males) as compared to 35 untreated controls (being 21 females and 14 males), **p = 0.0080. b The treadmill test shows that the average activity rate (means ± SE) is increased in a group of 17 IG treated mice (being 11 males and 6 females) as compared to 15 untreated controls (being 12 females and 3 males), *p = 0.0165