Fig. 2.

IG therapy dampens inflammation, fibrosis and suggests regeneration in muscle tissue. H&E staining shows that IG treatment decreases muscle inflammation and lesion and suggests muscle regeneration and PSH staining indicates less collagen fibers deposition in IG treated muscles. Panels a–d are from quadriceps muscle (a and b are H&E staining, control and IG; c and d are PSH staining, control and IG, respectively). Panels e–h are from gastrocnemius muscle (e and f are H&E staining, control and IG; g and h are PSH staining, control and IG, respectively). Panels i–l are from diaphragm muscle (i and j are H&E staining, control and IG; k and l are PSH staining, control and IG, respectively), scale bar = 100 μm, 20× magnitude for all images. For each muscle, there are three graphs in sequence assessing muscle quantification: percentage of inflammatory clusters; percentage of collagen fibers deposition within the tissue and the central nucleation index, respectively; * p < 0.05