Table 2.

Distribution of participants by number of activities and mean number of activities per patient, prompted by CMA and WGS for CMA non-diagnostic cases only and stratified by WGS result: all activities, lab tests, specialist and allied health visits

	Prompted by CMA			Prompted by WGS
	Category	N (%)	Mean (SD)	Category	N (%)	Mean (SD)
Total (n = 93)
All activities	0	77 (82.8%)	0.56	0	76 (81.7%)	0.62
	1–2	10 (10.8%)	(1.66)	1–2	10 (10.8%)	(1.98)
	3–4	3 (3.23%)		3–4	2 (2.15%)
	5 or more	3 (3.23%)		5 or more	5 (5.38%)
Lab tests	0	77 (82.8%)	0.55	0	85 (91.4%)	0.09
	1–2	10 (10.8%)	(1.64)	1–2	8 (8.60%)	(0.28)
	3–4	3 (3.23%)		3–4	0 (0%)
	5 or more	3 (3.23%)		5 or more	0 (0%)
Specialist and allied health visits	0	93 (100%)	0 (0)	0	85 (91.4%)	0.41
				1–2	2 (2.15%)	(1.60)
				3–4	3 (3.23%)
				5 or more	3 (3.23%)
WGS non-dx (n = 71)
All activities	0	57 (80.3%)	0.65	0	64 (90.1%)	0.11
	1–2	9 (12.7%)	(1.82)	1–2	7 (9.86%)	(0.36)
	3–4	2 (2.82%)		3–4	0 (0%)
	5 or more	3 (4.23%)		5 or more	0 (0%)
Lab tests	0	57 (80.3%)	0.65	0	65 (91.6%)	0.08
	1–2	9 (12.7%)	(1.82)	1–2	6 (8.45%)	(0.28)
	3–4	2 (2.82%)		3–4	0 (0%)
	5 or more	3 (4.23%)		5 or more	0 (0%)
Specialist and allied health visits	0	71 (100%)	0 (0)	0	71 (100%)	0 (0)
WGS dx (n = 22)
All activities	0	20 (90.9%)	0.27	0	12 (54.5%)	2.27
	1–2	1 (4.55%)	(0.94)	1–2	3 (13.6%)	(3.60)
	3–4	1 (4.55%)		3–4	2 (9.09%)
	5 or more	0 (0%)		5 or more	5 (22.7%)
Lab tests	0	20 (90.9%)	0.23	0	20 (90.9%)	0.09
	1–2	1 (4.55%)	(0.75)	1–2	2 (9.09%)	(0.29)
	3–4	1 (4.55%)		3–4	0 (0%)
	5 or more	0 (0%)		5 or more	0 (0%)
Specialist and allied health visits	0	22 (100%)	0 (0)	0	14 (63.6%)	1.73
				1–2	2 (9.09%)	(2.98)
				3–4	3 (13.6%)
				5 or more	3 (13.6%)

CMA chromosomal microarray analysis, dx diagnostic, SD standard deviations, WGS whole-genome sequencing