Table 2.

Effect cationic phospholipid DOTAP and DSPE-mPEG (2000) on entrapment efficiency (EE %), size and % release (R) in CUR/PTX loaded Niosomes

Code	Mole Tween 60 (%)	Mole cholesterol (%)	Mole DOTAP (%)	Mole PEG (%)	EE (%)	R (%)	Size (nm)	PDI	Zeta potential (mV)
F6	64.4	27.6	0	5	EE % CUR = 91.22 ± 0.28 EE % PTX = 86.11 ± 0.66	R % CUR = 38.53 ± 0.18 R % PTX = 31.44 ± 0.16	Size CUR = 91.5 ± 0.25 Size PTX = 118.9 ± 0.31	PDI CUR = 0.179 ± 0.23 PDI PTX = 0.164 ± 0.31	Zeta CUR = − 20.99 ± 0.45 Zeta PTX = − 19.24 ± 0.44
F7	59.5	25.5	10	5	EE % CUR = 98.24 ± 0.11 EE % PTX = 98.79 ± 0.24	R % CUR = 33.11 ± 0.33 R % PTX = 20.08 ± 0.44	Size CUR = 85.4 ± 0.43 Size PTX = 111.6 ± 0.24	PDI CUR = 0.177 ± 0.17 PDI PTX = 0.158 ± 0.24	Zeta CUR = + 14.83 ± 0.21 Zeta PTX = + 16.17 ± 0.31