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. 2018 Mar 23;16:28. doi: 10.1186/s12951-018-0351-4

Table 5.

Paclitaxel and curcumin combination index (CI) against MCF-7 and MCF-10A cells

Combination type MCF-7 cells MCF-10A cells
CI Interaction type CI Interaction type
Free paclitaxel + free curcumin solution 0.23 Synergistic 0.53 Synergistic
Paclitaxel niosome + curcumin niosome 0.35 Synergistic 0.53 Synergistic

CI < 1, synergistic; CI = 1, additive; CI > 1, antagonistic