Table 2.

Significantly enriched annotation clusters and functional terms

Annotation cluster 1	Enrichment score: 4.6
Category	Term	Genes	Corrected P value
SCR group B
GOTERM_MF_DIRECT	GO:0045028: G-protein coupled purinergic nucleotide receptor activity	P2RY12, P2RY13, P2RY14, GPR171, GPR87	3.7 × 10−7
GOTERM_BP_DIRECT	GO:0035589: G-protein coupled purinergic nucleotide receptor signaling pathway	P2RY12, P2RY13, P2RY14, GPR171, GPR87	1.3 × 10−6
GOTERM_CC_DIRECT	GO:0005887: integral component of plasma membrane	P2RY12, P2RY13, P2RY14, SLMAP, GPR171, PKD2, GPR87	0.790
GOTERM_BP_DIRECT	GO:0007186: G-protein coupled receptor signaling pathway	P2RY12, P2RY14, GPR171	1.000

Annotation cluster 1	Enrichment score: 2.7
Category	Term	Genes	Corrected P value
SCR group C
KEGG_PATHWAY	hsa04740: olfactory transduction	OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1, CNGA4	0.002
GOTERM_MF_DIRECT	GO:0004984: olfactory receptor activity	OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1	0.027
GOTERM_BP_DIRECT	GO:0050911: detection of chemical stimulus involved in sensory perception of smell	OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1	0.101
GOTERM_BP_DIRECT	GO:0007165: signal transduction	OR56A3, OR52B2, OR56B4, OR52L1, EVI2A, NF1, SMPD1, OR52W1, ESR1, APBB1	0.130
GOTERM_MF_DIRECT	GO:0004930: G-protein coupled receptor activity	OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1	0.163
GOTERM_BP_DIRECT	GO:0007186: G-protein coupled receptor signaling pathway	OR56A3, OR52B2, OR56B4, OR52L1, CCKBR, OR52W1	0.980
GOTERM_CC_DIRECT	GO:0005886: plasma membrane	OR52B2, CCKBR, MAP1B, NSFL1C, ESR1, OR56A3, OR56A4, OR56B4, OR56A1, OR52L1, SMPD1, OR52W1, MC3R, OMG, APBB1, FAM126B	0.964