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. 2018 Mar 20;131(6):643–647. doi: 10.4103/0366-6999.226892

Table 3.

Other variants involved in transcription regulation between MS and healthy controls

SNP Location* Region Candidate gene
rs228614 Chr4: 102657480 Intronic NFKB1/MANBA
rs11154801 Chr6: 135418217 Intronic MYB/AHI1
rs9321619 Chr6: 137553271 Intergenic OLIG3
rs4410871 Chr8: 127802783 Intronic MYC
rs4902647 Chr14: 68787474 Downstream ZFP36L1
rs2300603 Chr14: 75539214 Intronic BATF
rs744166 Chr17: 42362183 Intronic STAT3

SNP MS MAF (allele) HC MAF (allele) χ2 P OR (95% CI)

rs228614 0.48 (A) 0.48 (G) 1.005 0.361 0.864 (0.649–1.150)
rs11154801 0.36 (A) 0.35 (A) 0.067 0.796 1.040 (0.771–1.404)
rs9321619 0.36 (A) 0.39 (A) 0.559 0.455 0.894 (0.665–1.200)
rs4410871 0.30 (T) 0.34 (T) 1.205 0.272 0.842 (0.620–1.144)
rs4902647 0.30 (C) 0.33 (C) 0.648 0.421 0.881 (0.648–1.199)
rs2300603 0.31 (C) 0.27 (C) 2.139 0.144 1.260 (0.924–1.719)
rs744166

*Position is based on GRCh38.p10 and dbSNP Build 141; For Allele A. MS: Multiple sclerosis; HC: Healthy controls; SNP: Single-nucleotide polymorphisms; CI: Confidence interval; –: Not available; MAF: Minor allele frequency; OR: Odds ratio.