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. 2018 Mar 20;131(6):704–712. doi: 10.4103/0366-6999.226889

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Copyright: © 2018 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Adipose-derived stem cells-derived exosomes suppressed the expression of matrix metalloproteinases and promoted extracellular matrix synthesis in corneal stromal cells with Western blotting. Representative Western blotting images (a) and quantification (b) of the protein expression levels of ALDH, MMPs (MMP1, MMP2, MMP3, and MMP9), and collagen type I, II, III, IV, and V in CSCs and exosomes-treated CSCs (β-actin was used as the internal control). The bar graph shows the mean ± standard deviation in three independent transfection experiments. *P < 0.05 versus the CSCs alone. ADSCs: Adipose-derived stem cells; CSCs: Corneal stromal cells; MMPs: Matrix metalloproteinases; ALDH: Aldehyde-3-dehydrogenase.