Table 2.
Clinical and laboratory characteristics by survival
Parameter | Survived | Died | p valuea | ||
---|---|---|---|---|---|
# of patients | Median (IQR) | # of patients | Median (IQR) | ||
Age (months) | 84 | 45 (28.5–61.5) | 10 | 40 (33–66) | 0.99 |
Glucose (mmol/L) | 83 | 6.2 (4.6–7.3) | 10 | 5.9 (4.5–10.1) | 0.56 |
Haematocrit (%) | 83 | 20.4 (16.1–24.6) | 9 | 24.3 (17.7–27.6) | 0.34 |
White blood cell count (× 103 cells/µL) | 78 | 8.3 (6.4–12.9) | 9 | 11.0 (6.8–20.9) | 0.17 |
Platelet count (× 103 cells/µL) | 76 | 54 (33–83) | 9 | 31 (20–66) | 0.23 |
Lactate (mmol/L) | 82 | 5.9 (3.1–10.2) | 10 | 12.6 (8.1–14.9) | 0.005 |
Peripheral parasitaemia (× 103 parasites/µL) | 83 | 95.9 (25.0–283.9) | 9 | 49.6 (22.0–554.2) | 0.83 |
CSF PfHRP-2 (ng/mL) | 84 | 19.6 (4.0–48.0) | 10 | 54.6 (26.3–72.3) | 0.04 |
Plasma PfHRP-2 (ng/mL) | 84 | 9565 (3639–17,890) | 10 | 15,597 (3880–19,172) | 0.47 |
IQR, interquartile range
ap values are from Wilcoxon rank-sum tests