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TLR3-/- mice exhibit significantly reduced locomotor activity. Locomotor activity was assessed in 10-min epochs over the 90-min recording session in WT and TLR3 deficiency mice in 20 mg/kg (a), 10 mg/kg (b), 3 mg/kg (c) cocaine. *p <0.05, **p <0.01, n=12/WT groups, n=12/TLR3 KO groups. Data are presented as the mean ± SEM
