Table 2.
Effect of H2O2, GFJ, ARI induced alterations alone and in combination, on the levels of enzymatic and non-enzymatic antioxidant contents in serum of control and treated mice
| Treatment Groups | Group I Control | Group II H2O2 | Group III GF | Group IV ARI | Group V GF+ H2O2 | Group VI ARI+ H2O2 | Group VII ARI + GF + H2O2 |
|---|---|---|---|---|---|---|---|
| ALT (U/ml) | 40.07 ± 2.70 | 103.3 ± 3.40* | 36.98 ± 3.30 | 38.03 ± 3.90 | 69.42 ± 4.29 *# | 49.98 ± 3.43*# | 38.99 ± 3.29# |
| Protein (mg /ml) | 4.45 ± 0.90 | 2.08 ± 0.20* | 4.12 ± 0.19 | 4.57 ± 0.10 | 3.70 ± 0.70*# | 4.38 ± 0.30# | 4.98 ± 0.21# |
| BUN (mg/dl) | 43.07 ± 2.69 | 129.6 ± 4.10* | 41.50 ± 3.40 | 38.06 ± 2.80 | 73.86 ± 3.67 *# | 56.50 ± 2.85*# | 40.31 ± 3.28# |
| Creatinine (mg/dl) | 0.32 ± 0.03 | 0.58 ± 0.07* | 0.385 ± 0.06 | 0.285 ± 0.01 | 0.48 ± 0.08*# | 0.45 ± 0.04*# | 0.41 ± 0.06# |
| CK (U/ml) | 66.66 ± 5.30 | 52.6 ± 7.80* | 63.12 ± 5.20 | 68.28 ± 3.60 | 69.9 ± 8.70# | 71.9 ± 6.30# | 60.53 ± 4.9 |
* Statistically significant when compared to control group (P < 0.0001)
#Statistically significant when compared to H2O2 treated group (P < 0.0001)
Data presented as (mean ± SE) of three independent experiments and No. of animals (n = 10)