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3D-HPLC patterns of three Japanese herbal medicines and glycyrrhizae radix. The 3D-HPLC patterns of UKT (a), KSS (b), NSS (c), and glycyrrhizae radix (d) are shown. The constituents in the quadratic boxes possess phenolic and hydroxyl moieties, and those in the oval boxes might be convertible into active estrogenic constituents; i.e., liquiritigenin or isoliquiritigenin, through metabolic reactions
