Table 2.

Associations between demographic and clinical variables and presence of anti-PAD4 antibodies

	Univariate Models		Multivariable Model*
Variable	OR (95% CI)	p-value	OR (95% CI)	p-value
Female sex	1.1 (0.6–2.2)	0.74	0.9 (0.4–1.9)	0.74
Non-Caucasian Race	1.0 (0.5–1.9)	0.87	1.5 (0.7–3.2)	0.34
Ever Smoker	0.8 (0.5–1.4)	0.46	0.8 (0.4–1.4)	0.41
Disease duration > 10 years	3.6 (2.0–6.5)	< 0.01	3.5 (1.9–6.3)	< 0.01
Presence of Shared epitope	2.4 (1.3–4.3)	< 0.01	2.3 (1.2–4.5)	0.02

OR odds ratio, CI confidence interval; *model adjusted for disease duration, SE, race, smoking status, and sex