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. 2018 Mar 21;17:1533033818764470. doi: 10.1177/1533033818764470

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 7. — Wound healing potential of DFO-treated versus untreated cells: Disrupted MCF-7 treated with low- (A) and high-dose DFO (C) as well as MDA-MB-213 (E) cell cultures were photographed at 0, 6, 24, and 48 hours; and healing was qualitatively assessed by observing wound closure, migration of viable cells to wound area, and dead cells floating; data shown are representative of 2 separate experiments. Migration rates of viable cells into wound area in both untreated and DFO-treated disrupted MCF-7 (B, D) and MDAMB-231 (F) cell cultures were measured at 6, 24, and 48 hours using the formula: Migration rate = (mean width at 0 hours – mean width at time point (6, 12 or 24 hours)/mean width at 0 hours. *The presence of a statistically significant difference (P > 0.05) in rate of migration between treated cells and controls at the specified concentration/time point.