Table 4.
MI and complete case analysis of total HC+LP costs and QALYs and NMB (£20 k) at 6 and 12 months; by treatment group, all adjusted for baseline value, age, sex, baseline SCAS and baseline VAS
| SMC | SMC plus LP | Incremental difference | ||||||
| Mean | (SE) | n | Mean | (SE) | n | (95% CI) | n | |
| 6-month complete case | ||||||||
| Total cost (£) | 942 | (89) | 13 | 1563 | (127) | 21 | 621 (323 to 919) | 34 |
| QALYs | 0.252 | (0.021) | 22 | 0.259 | (0.016) | 32 | 0.008 (−0.057 to 0.073) | 34 |
| NMB at £20 000 per QALY | 4225 | (578) | 13 | 3762 | (461) | 21 | −464 (−1852 to 925) | 34 |
| 6-month imputed | ||||||||
| Total cost (£) | 1123 | (66) | 49 | 1517 | (54) | 51 | 394 (236 to 553) | 100 |
| QALYs | 0.247 | (0.015) | 49 | 0.274 | (0.014) | 51 | 0.026 (−0.015 to 0.068) | 100 |
| NMB at £20 000 per QALY | 3819 | (328) | 49 | 3954 | (276) | 51 | 135 (−733 to 1003) | 100 |
| 12-month complete case | ||||||||
| Total cost (£) | 1369 | (160) | 11 | 1814 | (211) | 16 | 445 (−57 to 947) | 27 |
| QALYs | 0.551 | (0.039) | 21 | 0.597 | (0.032) | 30 | 0.080 (−0.064 to 0.225) | 27 |
| NMB at £20 000 per QALY | 9454 | (1202) | 11 | 10 615 | (1113) | 16 | 1161 (−1966 to 4289) | 27 |
| 12-month imputed | ||||||||
| Total cost (£) | 1612 | (84) | 49 | 2002 | (67) | 51 | 390 (189 to 591) | 100 |
| QALYs | 0.533 | (0.025) | 49 | 0.628 | (0.021) | 51 | 0.095 (0.030 to 0.160) | 100 |
| NMB at £20 000 per QALY | 9042 | (521) | 49 | 10 551 | (427) | 51 | 1508 (148 to 2869) | 100 |
HC, health care; LP, Lightning Process; MI, multiple imputation; NMB, net monetary benefit; QALY, quality-adjusted life years; SCAS, Spence Children’s Anxiety Scale; SMC, specialist medical care; VAS, Visual Analogue Scale.