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. 2017 Dec 14;6:401. doi: 10.1038/s41389-017-0003-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Activation of JNK and p38 MAPK is impaired by MKP1 in glioma cells. a, b Representative western blot of the effect of overexpressing MKP1 in MAPK activity in (a) U87, U373 and (b) GNS166 cells. c Cell growth assay comparing control and MKP1-overexpressing GNS166 cells after 72 h of treatment with p38 MAPK inhibitor SB203580 (n = 3). d Cell growth assay of U87 cells comparing control and SB203580-treated cells for 72 h (n = 3)